Science first. Products later.

What is pullulan?

Pullulan is a natural polysaccharide formed by the fungus Aureobasidium pullulans when it ferments starch, for example from tapioca. It is used as a vegan capsule shell and is authorised in the EU as the additive E 1204.

What is pullulan made of and how is it produced?

Pullulan consists of maltotriose units (three glucose molecules joined by α-1,4 glycosidic bonds), and these units are linked to each other by α-1,6 glycosidic bonds. It is produced by fermentation: the fungus Aureobasidium pullulans converts starch-containing raw materials, often tapioca, into pullulan, which is then purified and dried. It is therefore plant-and-microbe derived, with no animal components.

On food labels it carries the number E 1204.

Pullulan capsules compared

Capsule shells for supplements are usually made from one of three materials:

Capsule materials compared

Typical properties, simplified.

Material
Gelatine
Origin
animal (bovine, porcine)
Vegan
no
Notable feature
classic, inexpensive
Material
HPMC (hypromellose)
Origin
plant cellulose, chemically modified
Vegan
yes
Notable feature
common vegan shell
Material
Pullulan
Origin
starch, via fungal fermentation
Vegan
yes
Notable feature
regarded as a good oxygen barrier

Why does the capsule shell matter?

The shell protects the contents from moisture and oxygen until the capsule dissolves in the digestive tract. Pullulan is regarded as a good oxygen barrier, which can be an advantage for sensitive ingredients. It does not make any health promise: the capsule is an excipient, not an active ingredient.

Curcumin+ from 2 Kapseln Bitte uses a pullulan capsule. Apart from the shell, the capsule contains only the curcumin–γ-cyclodextrin complex. Cyclodextrin is also derived from starch.

Food Supplements

Food supplements are foods that add nutrients or other substances in dosed form to complement the normal diet.

γ-Cyclodextrin

γ-Cyclodextrin is a ring-shaped sugar molecule of eight glucose units that can enclose fat-soluble compounds such as curcumin.

Curcumin

Curcumin is the yellow main active compound of the turmeric root: well studied, but fat-soluble and hard for the body to absorb.

Certificate of analysis (COA)

A certificate of analysis (COA) documents the lab testing of a batch for content and contaminants. How to read one and what makes it meaningful.